KINETICS OF THE ACETYLCHOLINESTERASE (AchE) INHIBITION
نویسندگان
چکیده
منابع مشابه
The acetylcholinesterase (AChE) inhibition analysis of medaka (Oryzias latipes) in the exposure of three insecticides.
The continuous effects on Acetylcholinesterase (AChE) activity of medaka (Oryzias latipes) caused by dichlorvos, methomyl and deltamethrin in vivo were investigated, and the trends of AChE activity inhibition due to the influence of these insecticides were discussed. The LC50-24h of dichlorvos, methomyl and deltamethrin on medaka were 2.3 mg/L, 0.2 mg/L, and 2.9×10(-3) mg/L respectively. The re...
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For decades the interaction of the anticholinesterase organophosphorus compounds with acetylcholinesterase has been characterized as a straightforward phosphylation of the active site serine (Ser-203) which can be described kinetically by the inhibitory rate constant k(i). However, more recently certain kinetic complexities in the inhibition of acetylcholinesterase by organophosphates such as p...
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Although fasting induces hepatic triglyceride (TG) accumulation in both rodents and humans, little is known about the underlying mechanism. Because parasympathetic nervous system activity tends to attenuate the secretion of very-low-density-lipoprotein-triglyceride (VLDL-TG) and increase TG stores in the liver, and serum cholinesterase activity is elevated in fatty liver disease, the inhibition...
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Rangoon creeper (Quisqualis indica Linn.) is a plant of the family Combretaceae. In Thai traditional medicine, its seeds contain oil and quisqualic acid that act as anthelminthic. Its flowers are used against diarrhea and eaten as vegetable. The flower extract gave high total polyphenol contents and showed strong antioxidant activity. In the search for new acetylcholinesterase inhibitors from p...
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Objective(s): The objective of this study was to evaluate pharmacological effect of Calligonum polygonoides against Krait snake’s venom acetylcholinesterase (AChE) and to extent it for the treatment of Alzheimer’s disease. Materials and Methods: Acetylcholinesterase activity was measured using Ellman method with some modification. The kinetic studies of methanolic extract of C. polygonoides aga...
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ژورنال
عنوان ژورنال: Indonesian Journal of Chemistry
سال: 2010
ISSN: 2460-1578,1411-9420
DOI: 10.22146/ijc.21939